Monday, February 2, 2026

The Effects of Taking Probiotics Alongside Antibiotics

The use of probiotics with antibiotics has been a topic of interest for many individuals looking to support their gut health while undergoing antibiotic treatment. Probiotics, which are live microorganisms that offer various health benefits, have shown promise in reducing antibiotic-related side effects such as diarrhea and the risk of Clostridioides difficile infection.

Recent research suggests that pairing probiotics with antibiotics may not have a significant effect on general gut microbiome balance and diversity, but they can still be considered in certain cases to prevent antibiotic-associated diarrhea. Studies have shown that taking probiotics with antibiotics can decrease the chance of diarrhea by about half and may lower the risk of Clostridioides difficile infection.

However, it is essential to consult a healthcare provider before starting probiotics, especially for individuals with a compromised immune system or certain medical conditions. The American Gastroenterological Association recommends specific probiotic strains for preventing Clostridioides difficile infection, but the safety and efficacy of probiotics with antibiotics may vary for each individual.

Overall, the use of probiotics with antibiotics may benefit those at a higher risk for Clostridioides difficile infection, such as individuals who have recently taken antibiotics for a long time, older adults, or those with a suppressed immune system. It is crucial to seek guidance from a healthcare provider before incorporating probiotics into antibiotic treatment to ensure safety and effectiveness.

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