Genetics may play a role in determining our lifespan, but a new study suggests that a healthy lifestyle can significantly offset any genetic predisposition to early death. According to lead author Dr. Xifeng Wu from Zhejiang University School of Medicine in China, individuals with a genetic risk for a shorter lifespan could reduce that risk by about 62% through healthy lifestyle choices.
The study, published in BMJ Evidence Based Medicine, analyzed data from over 350,000 people with European ancestry to explore the interplay between genetics and lifestyle factors. Participants were given a polygenetic risk score and evaluated based on their adherence to healthy lifestyle practices. The results showed that everyone, regardless of genetic risks, was 78% more likely to die early if they had an unhealthy lifestyle.
Dr. Aladdin Shadyab from the University of California San Diego, who was not involved in the research, praised the study’s methodology but noted its limitation in applying to diverse populations.
The researchers identified four key factors that had the biggest impact on the risk of early death: no smoking, regular physical activity, adequate sleep duration, and a healthy diet. Individuals with genetic risks could extend their lifespan by up to 5.5 years by following these lifestyle recommendations.
While the study was observational and could not establish causation, Dr. Wu emphasized the importance of lifestyle choices in mitigating genetic susceptibility to early death. He highlighted the benefits of an optimal lifestyle combination that includes factors like adequate sleep, regular exercise, and a healthy diet.
For those looking to adopt a healthier lifestyle, there are resources available such as phone helplines, apps, and support groups to help with smoking cessation and alcohol moderation. Embracing practices like the Mediterranean diet and establishing a sleep routine can also contribute to a longer, healthier life.
In conclusion, the study underscores the significant impact of lifestyle choices on longevity, offering hope to individuals with genetic predispositions for shorter lifespans. By making simple but impactful changes to their daily habits, individuals can potentially add years to their lives and improve their overall well-being.